منابع مشابه
Gluconeogenesis in the kidney cortex. Quantitative estimation of carbon flow.
Using analytical data and the results of degradation of glucose, lactate, and glutamate produced from [Z-14C]pyruvate or lactate, we have estimated the pathways of carbon flow during active gluconeogenesis in the kidney cortex. This approach involves a steady state model and solution with the aid of a digital computer. By the isotopic method one can estimate the rates of pyruvate carboxylase, p...
متن کاملGluconeogenesis in the isolated perfused rat kidney.
The perfused rat kidney was used for a study of gluconeogenesis. The kidney was completely isolated and perfused with Krebs-Henseleit bicarbonate buffer containing 5% albumin. Perfusion flow rate and pressure remained stable for 2 to 3 hours, although the glomerular filtration rate diminished with time. The fractional reabsorption of both water and sodium was 0.92 during the 1st hour of perfusi...
متن کاملAcceleration of gluconeogenesis from propionate by Dl-carnitine in the rat kidney cortex.
1. The rate of gluconeogenesis from propionate in rat kidney-cortex slices was stimulated up to 3.5-fold by dl-carnitine and by bicarbonate, and was inhibited by inorganic phosphate or high concentrations of propionate (above 3mm). 2. The stimulatory effect of carnitine was dependent on the bicarbonate concentration and could be replaced at low propionate concentration by addition of 25mm-bicar...
متن کاملRenal Gluconeogenesis. 2. the Gluconeogenic Capacity of the Kidney Cortex of Various Species.
2. There are specific repressor effects: galactose is an effective repressor for ,B-galactosidase but not for the other enzymes; conversely, pyruvate represses tryptophanase and serine deaminase but not ,-galactosidase. 3. In wild-type E. coli glucose represses all three enzymes. A mutant has been selected in which there is no glucose effect for any of the enzymes but in which each enzyme remai...
متن کاملRole of kidney in gluconeogenesis and amino acid catabolism.
SZEPESI, B., E, H. AVERY, AND R. A. FREEDLAND. RoZe of kidney in gluconeugenesis and amino acid catabolism. Am. J. Physiol. 2 19 (6) : 1627-1631. 1970--The enzyme profiles of rat liver and kidney were studied in five different conditions: a) high-carbohydrate, protein-free diet, b) high-carbohydrate (adequate protein) diet with or without exogenous hydrocortisone, and c) high-protein, carbohydr...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1972
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)44761-3